Tag Archives: clinical data management

How Clinical Research Management Can Help You?

A scientific analysis manager conducts analysis, investigations and tests of protocol subjects and participants. Their responsibilities consist of collecting data and monitoring the results of the scientific tests. Clinical analysis planners also collaborate with other medical managers in the implementation of scientific tests and the recruitment process of medical trial participants.

Work Experience

To become a scientific analysis manager, applicants for these positions should have prior encounter as scientific analysis experts. Understanding the scientific analysis process and participating in scientific tests are important attributes that companies may need applicants for the job to have. The degree of scientific analysis encounter needed to qualify for a job as a scientific analysis manager is determined by the companies. Some companies may need only one to two years of scientific analysis encounter, while other companies pursue individuals with additional years of encounter.

College Education

Many companies may seek applicants for the scientific analysis manager place who possess an associate’s or bachelor’s degree in scientific analysis. Having a degree in scientific analysis, coupled with less than one to two years of expertise in scientific analysis, may meet adequate minimum qualifications with some companies.

Because scientific analysis planners prioritize and oversee the development and implementation of scientific analysis tests, many companies need them to be licensed as a registered nurse or a licensed practical nurse. Many companies who seek applicants with an RN or LPN license may also need them to have at least one year or more nursing expertise in a medical facility.

Certification

Certification also benefits applicants for scientific analysis manager positions, and some companies need applicants to have a documentation in scientific analysis from approved organizations that offer documentation courses and examinations. The Society of Clinical Research Associates and the Association of Clinical Research Professionals are nationally recognized organizations that offer documentation programs for scientific analysis experts.

Additional Qualifications

Many companies need individuals to be proficient with Microsoft Word, Excel and Outlook. Interpersonal communication skills and encounter working in a team environment are skills needed for this job place. Strong organization and prioritization skills are also beneficial skills that companies may need applicants to possess for the scientific analysis manager place.

Supervisory Role

Many scientific analysis experts become promoted or advance to the higher level supervisory positions after gaining additional qualifications and expertise in scientific analysis. Clinical analysis planners oversee the entire process of scientific analysis investigation and tests and ensure that all medical experiments and tests are compliant with the objectives of each project. Clinical research management is a wonderful field and you can choose to make your career in this field.

Related Posts:

1)6 Ways ResearchKit Would Change Clinical Research

2)Top 10 Clinical Research Interview Questions

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

Clinical research for Hair Treatment

Clinical research for Hair Treatment

Treatments for the various forms of losing hairs have on moderate success. Three medicines have proof to back up their use in hair thinning locks loss: finasteride, dutasteride and minoxidil. They generally work better to prevent further losing locks than to replenish lost locks.

They may be used together when losing hairs is progressive or further restoration is desired after 12 several weeks. Other medicines include ketoconazole, and in female androgenic hair loss spironolactone and flutamide. Mixtures of finasteride, minoxidil and ketoconazole are more efficient than individual use.

Finasteride

Finasteride is used to treat hair thinning losing locks. Therapy provides about 30% improvement in losing locks after six several weeks of treatment, and effectiveness only continues as long as the drug is taken. There is no good proof for its use ladies.

It may cause man boobs, male impotence and depression.

Dutasteride

Dutasteride is used off label for hair thinning losing hairs.

Minoxidil

Minoxidil, applied topically, is widely used for the treatments for losing locks. It will work in helping promote growth of hir in both individuals with androgenic hair loss. About 40% of men experience growth of hir after 3–6 several weeks. It is the only topical product that is FDA approved for androgenic losing locks.

Ketoconazole

Ketoconazole may help ladies.

Spironolactone

There is tenative assistance for spironolactone ladies. Due to its feminizing adverse reactions and risk of sterility in men it is not often used in men. It can also cause hypotension, hyperkalemia, and cardiac dysrhythmia. Also, ladies who are expecting or trying to conceive generally cannot use the medication as it is a teratogen, and can cause uncertain genitals in infants.

Flutamide

There is preliminary proof for flutamide in women; however, it is associated with relatively high rates of liver problems. Like spironolactone, it is commonly only used ladies.

Certain hair shampoos and conditioners and creams creatively become thick current locks, without having affected the growth pattern. There have also been improvements in the style industry with wig design. The ornament has also been proven a source of emotional support for females going through radiation treatment, with melanoma heirs in one study explaining their wig as a “constant companion”. Other research in ladies have confirmed a more combined psychosocial effect of hairpiece use.

Specialized head tattoo designs can simulate the overall look of a short buzzed haircut. Clinical research management has always a very good scope and you can make your career in this field.

Related Topics:

1)Requirement of Clinical Research Associate

2)What is the responsibility of a clinical research associate?

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

What Are the Steps Related to Clinical Assessments?

Clinical assessments are a type of analysis that involve huge numbers of individuals order to test new therapies. Many, but not all analysis, are assessments.

Clinical analysis aim to find out important info in response to any adverse wellness question in a very methodical way. A well designed analysis will provide efficient evidence that can help improve NHS services and therapies and the healthcare understanding of doctors.

To be efficient it usually involves obtaining wellness details from a variety of individuals whose healthcare concerns fit the topic of the study. Where sufferers agree, or “consent”, to join as volunteers, this details might be obtained by:

  • Interviews
  • Questionnaires
  • Tests on sufferers in a healthcare setting that measure the effects of new drugs
  • Using individual records
  • A combination of the above

If you are interested in becoming a individual in research:

You could ask your GP or Advisor to consider any assessments or analysis that you may be suitable for You could check out the web pages for your local Clinical Research Network

You could check out the The UK Clinical Trials Entrance which provides details about scientific analysis assessments running in the UK

The NHS Structure says that your NHS healthcare professional should inform you of any analysis for which you may be eligible. ‘Eligible’ here concerns how you fit the strict healthcare and personal requirements used in the study design for it to work technically.

Think about it for a time that you are a effective psycho therapist. Cynthia comes to see you because she’s having a problem. How do you cure her? How do you even know incorrect with her?

Clinical assessment is a way of identifying and preparing treatment for a individual that includes analyzing someone in order to determine incorrect. There are several kinds of emotional tests, all of which have their own pros and cons.

What’s the point of assessment? To response that, let’s go back to the time that Cynthia walking into your workplace. She informs you that she’s sensation very pressured out and nervous because she keeps failing to remember factors. She used to be really up to the mark, but lately she has problems keeping in mind where she sitting her car or what she did just a couple of moments ago.

What’s incorrect with Cynthia? There are several factors that can cause forgetfulness. The only way that you can find out incorrect with her is to do some kind of assessment. Medical tests help you, the psycho therapist, to know what might be resulting in trouble for your individual. Clinical assessment example can be related to psychology.

Related Topics:

1)Requirement of Clinical Research Associate

2)What is the responsibility of a clinical research associate?

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

First in Human (FIH) Clinical Trials

First in Human (FIH) Clinical Trials

First this first, you must know what FIH is as all FIH trials are not the same. FIH trials are basically conducted with 20-80 study volunteers. The objective is to find the metabolism and pharmacologic action of a test drug in humans, the side effects that might be associated with increasing doses, and if possible gain early evidence on effectiveness.

In simple terms, FIH studies give researchers a base to understand the safety of the drug and might also show the action mechanism in humans.

Not an easy job

Nothing is so easy, there is Phase I studies that deviate from the FIH Phase I cookie-cutter norm, such as:

  • Clinical trials in which volunteers receive one of the following types of test drugs:
    1. A new compound in a novel drug class

    2. A novel compound in a drug class that is being through human testing with a different IND

    3. A novel drug/approved drug combo

    4. An approved drug with a novel formulation or changed dose

  • Clinical research requires a special population of age or type.
  • Clinical trials for which the drug is therapeutic

Each FIH trial should be evaluated on an individual basis because the objectives and risk factors vary. The preclinical data, trial design, proposed population, and safety measures must be evaluated for every FIH trial.

What part does the CRO play?

The CRO plays a vital role. They are to offer their expertise to make sure the successful completion of the clinical trial.  

CROs experienced in the conduct of FIH studies are knowledgeable and equipped to guide sponsors through the process of designing the best possible protocol. They conduct studies for the whole day, starting from Monday to Sunday. They would tell you about recruitment, if your blood draw times are feasible, and if your timelines are realistic.

A team with general or late phase clinical research expertise is not sufficient.

It is essential that the Chief Investigator and the study team have a lot of experience conducting FIH trials and possess the qualifications to make sure that the trials go smoothly. The clinical team is vital in ensuring that the protocol is optimal with little scope for amendments or deviation, while also making sure recruitment goals can be met, even with the most strict inclusion/exclusion criteria. Whether it’s a simple Single Ascending Dose (SAD) trial or a complex, adaptive design, the team conducting the study is a pivotal factor to success.

When it’s time to outsource a clinical trial to a CRO, it’s best to find out how involved the principal investigator (PI) and sub-investigators will be. Moreover, the experience of project managers, study coordinators, lab personnel, data managers, and medical writers are equally important. The PI is responsible for supervising the staff; however, problems can arise when a PI is either an inexperienced or uninformed in conducting FIH trials or puts too much responsibility on the staff to perform tasks that the PI should be overseeing.

In short, an experienced CRO can minimize the risk of recruitment and retention issues look after the safety concerns, bad data and a whole list of other issues that could halt your FIH clinical trial.

Does your CRO have what it takes?

You need to look into the matters discussed above and have your words with your consultant to know hoe efficient your CRO is.

We conclude the discussion here.

In the competition of many organizations CRB Tech Solutions developed a good name. It has earned a name in offering the best training in Clinical Research.

Clinical research jobs in Pune are increasing and to meet the current requirement of the proficient candidates, you should consider enhancing yourself with our clinical research training program.

The Clinical Research review by CRB Tech Solutions will guide you in considering a clinical research career in this field.

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

Interview For Pharma Freshers : Tips & Preparations Part II

Interview For Pharma Freshers : Tips & Preparations Part II

Today we continue with the same topic we were discussing in our previous blog post.

Interview tips

The three aspects of the interview process:

  • Pre-Interview Planning
  • Interviewing
  • Following-up

PRE-INTERVIEW PLANNING

This will make you more confident and keep you motivated. Before you start keep a written or computerized list:

  • Date resume was sent
  • Name of company
  • Name of person you sent it to
  • Address
  • Phone
  • Date and time of interview
  • Results of interview
  • Second interview
  • When you sent a thank you letter or note

You need to find about the company thoroughly, which is very essential but it is often neglected. Try finding out the following information:

  • Products or services
  • Company history
  • Number of employees
  • Business methods
  • Distribution methods
  • Organizational structure
  • Clients or customers -Locations
  • Reputation
  • Philosophy
  • Industry standing/ Sales or activity volume
  • Prospects for company growth

INTERVIEWING

You need to relax and think about all of your skills, accomplishments, and abilities. You should know your strength and weakness. You need to make a resume that would say everything about in details and must be appealing.

Resume

  • Be honest.
  • You need to quantify your achievements with figures and percentages
  • You must think in terms of increasing productivity, decreasing costs, and increasing profit for the company.
  • Try to appear relaxed and alert
  • Be friendly and an enthusiast.
  • Always dress in your formals and be calm in your look.
  • First impressions counts.
  • Groom yourself well.
  • Sit comfortably and with good poise.
  • Ask questions. If you want to clarity certain aspects of the job.
  • Don;’t ask about paid holidays and vacations unless the job is offered
  • Carry extra resumes and references with you.
  • No fancy jewelry please.
  • Be polite.
  • Show a can-do and positive attitude.
  • If asked general questions, answer in terms of your professional abilities and experiences.
  • Never, never criticise former employers.
  • Have good posture and direct eye contact.
  • Give a firm handshake before and after the interview
  • Speak clearly in a firm, confident, and not too loud voice
  • Smile, when appropriate
  • Try to relax
  • Give specific answers to all questions. Don’t be vague.
  • Thanks the interviewer.
  • If you are really keen for the job, tell the interviewer again before you take your leave.

EMPLOYERS INDICATE THAT YOU CAN HURT YOUR CHANCES OF GETTTNG A JOB BY :

  • Poor career plans
  • Under qualified for the position
  • Communication not proper
  • Unsatisfactory evidences of achievement
  • Fail to research the company
  • Displaying a lack of interest in the organization
  • Unwillingness to relocate
  • Appearing more interested in money and benefits than anything else
  • Fail to follow-up post interview

THE GOLDEN RULE OF INTERVIEWING:

Be yourself, know yourself, and sell yourself.

Employers are looking for someone who can contribute to the buisiness by:

  1. Making Money
  2. Saving Money
  3. Saving Time

So keep it in mind.

WE conclude the discussion now. You have to prepare by your own and crack your interview confidently.The above tips are very essential to keep in mind. Good luck!

In the competition of many organizations CRB Tech Solutions developed a good name. It has earned a name in providing the best training in Clinical Research.

Clinical research jobs in Pune are increasing and to meet the current demand of the proficient candidates, you should consider improving yourself with our clinical research training program.

The Clinical Research review by CRB Tech Solutions will help and guide you in making a clinical research career in this field.

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

21 Trends for Nurse Practitioners in 2016 Part II

21 Trends for Nurse Practitioners in 2016 Part II

Today we continue with the blog topic we started a few days back and shall discuss some other points that is making nurse practitioners trending in 2016.

Here I’m discussing a few more and the many more shall be covered in our upcoming articles.

Integrated Care

In 2015, great initiatives were taken in integrating primary care and psychiatric care. The common venture of both the Mental Health Parity and Addiction Equity Act and the Affordable Care Act created the perfect blend to help integration. The new payment models reward healthcare providers for improving patient outcomes while making an effort in reducing overall costs and research. This is what integrations can achieve.

Empowered Patients

The thoughts and views of patients are given a better and more priorities. Now patients can make of use the internet to compare hospitals and select the one with the best clinical prospects, safety measures, and competitive costs. Patients are actively making use of this benefit and choose their healthcare facilities and providers wisely. Thus the well informed patient has become an empowered patient.

Wellness & Employee Health

Now more and more insurance payers and large organizations seek to bear health care costs under the Affordable Care Act. Though similar programs existed earlier, they have currently begun to gather considerable traction. Businesses are now offering their employees free gym memberships, free health screenings, massages, mid-day yoga breaks, smoking cessation classes and weight loss resources.

Bundled Payments

In the year 2015, the Centers for Medicare and Medicare Services announced a number of payment reform models in which they proposed to authorise bundled payments for total hip and total knee replacement in 75 different geographic areas across the region.

This proposal came as a shock for a few medical groups because for the first time, the concept of bundled payments would become a requirement and not voluntary. As 2016 progresses, let’s keep a watch on the outcomes and can anticipate more unique payment models yet to be announced.

ICD-10

The US ultimately implemented the International Classification of Diseases, 10th Edition (ICD-10) on October 1, 2015, to become the last modern healthcare system in the world to adopt this more effective coding system. Originally started by the World Health Organization (WHO) in 1992, ICD-10 designed a coding system that classifies diseases and other health issues such that diagnostic information can be easily stored and retrieved.

Greater Accountability

Now an era of accountable care has begun with the already existing healthcare. Hospitals are now accountable for their patient outcomes and there is forming of Accountable Care Organizations. It’s mandatory for hospitals to demonstrate to the public exactly how and how well they are implementing evidence-based practices. They must also submit reports to the federal government, which then becomes open to the public.

With time, CMS is becoming more and stricter regarding the delivery of accountable care. Those organizations that fail to meet CMS’s criteria are subjected to reimbursement reductions. In the coming years, CMS is likely to increase the penalties and holding the hospitals more accountable for delivering high-quality care.

Now we conclude here. Hope the discussion is giving the right and precise information to you.

Stay connected with us for more discussions to come. Let us know your experience with us in the comment sections below.

In the competition of many organizations CRB Tech Solutions developed a good name. It has earned a name in providing the best training in Clinical Research.

Clinical research jobs in Pune are increasing and to meet the current demand of the proficient candidates, you should consider enhancing yourself with our clinical research training program.

The Clinical Research review by CRB Tech Solutions will guide you in considering a clinical research career in this field.

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

How Scalable Is Your Clinical Trial Payments System

How Scalable Is Your Clinical Trial Payments System

Today in this blog topic we shall discuss about ClinPay a payment solution initiated by Bioclinica and is being very helpful to the Clinical Research Organisations worldwide.

How Scalable Is Your Clinical Trial Payments System

Bioclinica came up with this alternate payment option to help CROs that have outgrown their site payment systems. Whether they’re using manual home-grown system or spreadsheets with the increase in number of clinical trials they’re conducting, the CROs often find it difficult and a realisation that the current systems are not sufficient.

It is very important to maintain accurate and timely payments and as a result, it’s important to choose a payments solution that is scalable, in other words it should be an automatic one as opposed to the manual. ClinPay is a part of the suite of Bioclinica products designed to automate the entire financial lifecycle of global clinical trials, which includes contract management, contract term translation, payments, accounting and reporting functionality. ClinPay can significantly reduce workload and operational costs, make an access to clinical research payment information, and enable multi-currency management. To mention that ClinPay is very much data-driven and automatically evaluates incoming data against contract terms in order to determine a wide variety of payments, which says that no matter how vast your study is, how many sites you possess or how you payment terms, ClinPay can scale to fit your needs.

Let’s share an example for a big CRO who has found success after switching from the manual system to an automated. A top CRO grew significantly within a span of short period of time, making the investigator payments process a significant and admin-intensive challenge. To mention the 100 team members were given the task to hand just grant payments. The CRO does 350 to 400 global trials at a given time, and hence was becoming difficult to make payments to sites in time and in accurate ways. As a result, the CRO was flown with complaint mails and messages from sites about payments, which lead to bad relationships with the sites as well as sponsors. The CRO realised that their manual payments model wasn’t automatic, and they needed to do the technology way and find a technical solution to keep pace with their growth.

After discussing and reviewing many good financial management solutions, the CRO decided to give ClinPay a try because it was the only end-to-end solution that could manage all the unique challenges and characteristics of a clinical process. The CRO was also particularly interested in ClinPay’s ability to make global payments and knowing of country-specific requirements. Additionally, the CRO wanted to use ClinPay to pay their sites accurately and on time as well as achieve a significant amount of financial savings. Finally, the CRO wanted to use ClinPay to enhance efficiency with their clinical research team so that team members could focus more on the trials and less on site payments.

Now the story is that by using ClinPay, the CRO has well organised their process, gained remarkable efficiencies and allowed many of their team members to focus on more vital tasks.

We conclude.

Please let us know your opinion in comment section below. Readers’ opinions are valuable! A good discussion is the gateway to many innovations and ideas.

In the competition of many organizations CRB Tech Solutions developed a good name. It has earned a name in providing the best training in Clinical Research.

Clinical research jobs in Pune are increasing and to meet the current demand of the proficient candidates, you should consider enhancing yourself with our clinical research training program.

The Clinical Research review by CRB Tech Solutions will guide you in considering a clinical research career in this field.

Related Posts:

1) Why Clinical Trials Are Very Much Useful Through Mobiles?

2) Clinical Trials and Its 4 Stages for New Medications

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

Myths and Reality Of EDCS In Clinical Data Management

Myths and Reality Of EDCS In Clinical Data Management

Today in this blog topic we would discuss EDCS and its utility in CDM i.e. Clinical Data Management. EDCS is the acronym for Electronic data capture System.

EDC is very common in usage in clinical study yet there are so many myths and misconceptions surrounding the move from conventional, paper-based clinical data input to EDC. The only fact is that EDC technology more the cloud-based systems are comparatively a recent addition to the clinical research industry.

Though EDC is no longer a novel object, yet it is too young to be embraced as the next industry standard. EDC is caught somewhere in between.

Here we discuss the myths surrounding with it and how to overcome them.

Myth 1: EDC is expensive

Reality: EDC cuts down study costs

Some EDCS are pricey to install, train the staff and implement, but the overall budget during the study and after the study cannot be underlined. Sponsor ROI for switching to EDC is well worth the initial investment.

The very thought that EDC is expensive is a remnant of the early history of EDC. When the technology was first initiated, as with any first generation thing, the more capable the system was the more expensive it was. EDC vendors are now available, all competing to overtake in performance the other guys and that too in the most attractive price point.

Myth 2: Switching to EDC involves too much time

Reality: EDC is very precious to study time

This myth has been true when EDC got first rolled out for clinical trials, but it is entirely a baseless argument today. To mention, 80% of the time and money spent on pharma development is spent on repetitively conducting clinical trials. For your information, EDC allows both for an attractive cost ROI and time ROI too.

On an average, EDC cuts 41% of pre-study preparation time.

Myth 3: Data stored in the cloud is unsafe

Reality: Cloud storage is comparatively more secure than on-site and/or paper

We all know and heard about the urban style of cyber theft. We hear horror stories of identity theft, hacking of bank accounts, etc. Always an exception exists for the rule; data storage for the most of of cloud systems is protected with huge and redundant security protocols against loss, theft or corruption of integrity. 

Myth 4: EDC is meant for massive Phase III+ studies

Reality: Studies of every size can take advantage of EDC

Though the origin or initiation of EDC was done keeping larger studies in mind like phase 3 clinical trials or later, but currently there are systems present to match every varying degree of study be it simple ones or complex. Of course, the longer the duration and greater the number of variables measured will explain the actual value of switching to EDC.

To mention EDC systems are very much customizable. If your next clinical venture is going to have more or less data than the previous study, your EDC vendor can work with you to customize the system as per requirement, so your team does not need to spend time and effort to source another vendor.

What are the possible disadvantages of EDC for CDM?

To be honest, there is not a single scenario where EDC does not defeat or is a better choice than paper-based data management in terms of savings of time and money. EDC is even “green” compared to conventional data capture methods.

We conclude.

Please let us know your opinion and views on EDC and its usage in CDM in the comment section below.

In the competition of many organizations CRB Tech Solutions developed a good name. It has earned a name in providing the best training in Clinical Research.

Clinical research jobs in Pune are increasing and to meet the current demand of the proficient candidates, you should consider enhancing yourself with our clinical research training program.

The Clinical Research review by CRB Tech Solutions will guide you in considering a clinical research career in this field.

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

What To Do When An Outsourced Clinical Trial face A Crisis

What To Do When An Outsourced Clinical Trial face A Crisis

Today in this blog topic we would discuss outsourcing in clinical research and how to find a solution if an outsourced clinical trial hits a roadblock.

In the 1990s and 2000s, outsourcing already revolutionized the IT industry and experts have a belief that outsourcing has the power to revolutionize scientific research in the very same way. But under present situation, outsourcing in science is very difficult. It’s hard to find providers and is hard convincing them and also difficult to evaluate them and pay them. Well other industries solved these barriers by creating a marketplace, but the question is whether same solution is applicable to scientific researchers also?

Well Science Exchange can make makes outsourcing easy and wondering how many more discoveries can be made when scientists will be able to tap into the best resources. A very exciting thought!

But the fact is that keeping clinical trials on schedule is not an easy task. Whether a sponsor face issues with timeline, quality, personal or plenty of other things with an outsourced partner, it’s critical to address the problems as soon they arise. You are right we are making mention about the barriers that can be faced in clinical outsourcing.

When a clinical study hits a roadblock, there are a few options that can be addressed. One choice is to have a 3rd party interference, evaluate the situation, and oversee the original partner until study completes. Another option is that a 3rd party rescue where the study is taken over completely.

But while you take the decision about which option you should go for that would be best for your company, consider the following:

  • How fast does the database lock need to occur? If the DB Lock date has some good time remaining, it could be best to have a 3rd party come to the rescue. But, if only a couple of weeks are left, transferring the study is probably not a good idea; this might push away the timelines out even further and increase costs. In such situation, the best solution might be to let the study be where it is, but get a 3rd party come in and take the charge.
  • Who possess the database? If your database is with the organization which initially contracted to conduct the study then moving it to another company could pose a significant challenge, as that alone needs more time and money. But if your study is being carried out by a company provides study and rescue operation, handing the task to them is often the wisest decision.

It is quite obvious that a sponsor choose a partner seeing on the monetary aspect and if the partner fails to keep the words! Over the years, two key lessons surfaced about outsourcing: (1) Need to give extra attention to the data quality produced by the partner, and (2) never accept words that appears very true and too good.

So keep the above mentioned points in mind while selecting your outsource partners, and there will be better chances of avoiding barriers in your research study.

We conclude here. Hope you liked the discussion let us know your opinion in the comment section below.

In the competition of many organizations CRB Tech Solutions developed a good name. It has earned a name in offering the best training in Clinical Research.

Clinical research jobs in Pune are increasing and to meet the current requirement of the proficient candidates, you should consider enhancing yourself with our clinical research training program.

The Clinical Research review by CRB Tech Solutions will guide you in considering a clinical research career in this field.

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter

Seeking HIV Treatment Clues In The Neem Tree

Seeking HIV Treatment Clues In The Neem Tree

Neem tree or the village pharmacy is being currently being researched to seek remedy for Aids treatment. As a child we were always said about the medicinal values, now the world is trying to find out its special advantage in fighting the smart mutant virus called HIV.

Currently an assistant professor at Kean University in New Jersey, Arora is trying to understand the curative properties of the neem tree in fighting the deadly virus that causes AIDS. With her research work she presented the found data at a poster session on April 22, at the Experimental Biology 2012 meeting in San Diego. The initial results indicate about compounds in neem extracts which target a protein that helps HIV to replicate. If further research is being done with her findings, Arora’s work might give a novel drug to the world that is deliberately fighting with HIV-Aids.

As a Botany student I read about the neem extracts from leaves, bark and flowers which are used throughout the Indian subcontinent to fight against pathogenic microbes. It is also known to that the branches are used and not the duo toothpaste and toothbrushes to keep teeth and gums healthy, and neem extracts are popularly used to prevent the spread of malaria.

Even early practitioners mentioned in Ayurved books and scripts about the medicinal value of neem. It is actually regarded as a type of traditional Indian alternative medicine. There are treatments in which neem extracts are prescribed along with other herbs, to treat heart diseases and control diabetes. The neem tree, with scientific name Azadirachta indica belongs to the mahogany family, which also grows in eastern part of Africa.

Arora’s academic training gave her an expertise in the cellular biology of Oncology, Pharmacology, Bioinformatics and Physiological biology. In 2008 when she set her laboratory with a novel and innovative ideas and direction at Kean University, Arora was determined to combine her knowledge with her long-time penchant for natural products. The neem tree is one of her first choice.

Arora explored into the vast ocean of scientific literature to find what was already known about neem extracts. During that endeavour, she came across two reports that depicted that when HIV-AIDS patients in India and Nigeria were given neem extracts, the amount of HIV particles in their blood got reduced. Overwhelmed, Arora wanted to see if she could find out what component in the neem extract could be fighting off the virus.

She made use of her knowledge to bioinformatics and structural biology to see what she could find by making computer models of HIV proteins with compounds present in neem extracts. By reviewing literature, she and her pupils found 20 compounds present in various types of neem extracts. When they tried creating model for these compounds against the proteins crucial for the HIV life-cycle, Arora and her team discovered that most of the neem components attacked the HIV protease, a protein required for making new copies of the virus.

Arora’s team is now working on experiments with test-tube to find if the computer models are similar to actual samples. If her effort succeeds and her assumptions materialise out, Arora thinks that neem tree will give a cheaper and easier way to fight the HIV-AIDS rise in developing countries, where current therapies are too costly for the general or lesser mass.

We conclude here.

In the competition of many organizations CRB Tech Solutions developed a good name. It has earned a name in offering the best training in Clinical Trials.

Clinical research jobs in Pune are increasing and to meet the current requirement of the proficient candidates, you should consider enhancing yourself with our clinical research training program.

The Clinical Research review by CRB Tech Solutions will guide you in considering a clinical research career in this field.

Don't be shellfish...Digg thisEmail this to someoneShare on FacebookShare on Google+Buffer this pagePin on PinterestShare on LinkedInShare on RedditPrint this pageShare on StumbleUponShare on TumblrTweet about this on Twitter