Monthly Archives: August 2016

Research Areas in the Clinical Psychology

Clinical psychology research is very significant to the nation’s health and well being as other clinical research. It works in the same way as the same way as clinical scientists try to understand the prevention and spread of different genetic and infectious diseases, scientists conduct rigorous psychological research studies to comprehend , prevent, and treat the human condition as it applies psychologically to individuals,families and diverse communities.

Factual results gathered from psychological research studies help practitioners in developing effective interventions and techniques that clinical physicians execute proven, reliable results that improve lives, help troubled relationships, help addicts, and help manage and treat a variety of other mental health issues.

In order to evaluate this body of research, clinical psychology students must undergo proper clinical research training to make significant professional contributions to the field , staying current and up-to-date with the research taking place at universities and research labs across the world. Doing research, investigating unique ways to understand the human mind, and finding solutions to enrich the lives of all others.

Most of these research studies basically fall within one of three main areas integral to clinical psychology:

Assessment

An important aspect of clinical psychology research, involves assessment – or producing significant and reliable tests. Assessments take the form of written tests e.g. intelligence tests, vocational tests and other tests created to measure aptitude for specific careers, interests, and personality types.

Clinical psychologists interview individuals, review their medical data, and conduct clinical trials as part of the assessment process. A comprehensive assessment approach confirms that psychologists apply the most effective and appropriate psychological treatments and interventions.

Roberts and Hardi stated that measurement of treatment procedures, treatment integrity, behavioral changes, functional performance, objective measurements, change of perceptions, and satisfaction from a variety of sources, follow-up assessment, etc., are needed to finalize the ‘scientific credentials’ of each therapeutic approach.

Diagnosis

After gathering sufficient data, they consult the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-R), which lists criteria and generalized definitions for mental illnesses and conditions. Categories of symptoms differentiate one mental illness from another, and the basic course of each illness.

Beyond the DSM-IV-R, however, research in the field of diagnosing mental health problems remains one of the most exciting research areas in the field today – thanks to rapid advances in technology. Numerous techniques of brain imaging that map brain structure and function now give researchers “images” of both normal and unusual brain functioning. Scientists are using CT, MRI and PET to come up with greater accuracy in diagnosing various mental illnesses.

Psychotherapies

A set of procedures or techniques that psychological problems, and come up with different ways of thinking, behaving, or feeling – has exploded in popularity since the middle of the last century. Most psychotherapies come within one of the four main psychotherapeutic frameworks:

Psychodynamic Therapy

Psychodynamic therapy discovers an individual’s unconscious, seeking reasons or explanations for the individual’s present behavior. This treatment, also called insight-oriented therapy, attempts to bring underlying factors grounded in beginning life to the individual’s attention, increasing self-awareness and self-understanding.

Psychodynamic therapy originates from Sigmund Freud’s psychoanalysis, making it the most old form of psychotherapy. As a result, a large body of research exists to either help or refute the effectiveness of this approach.

Because the results of psychoanalysis research are difficult to measure than behavioral-oriented therapies, research methodologies and outcomes of treatment have been questioned – especially those of the previous studies.

Psychodynamic therapy requires long-term treatment, sometimes a year or more, also complexing the research process. However, researchers today apply the most rigorous scientific processes, including statistics studies completed over a number of years, to study of efficacy of psychodynamic practice and techniques, and many studies report significant positive outcomes.

In the race of many institutes CRB Tech Solutions has created its own niche. Its very popular in offering the best training in Clinical Research. Our clinical research institute has created a niche for itself in this field.

Clinical research jobs are increasing gradually and to meet the emerging need of efficient professionals , you should consider upgrading yourself with clinical courses.

The Clinical Research review by CRB Tech Solutions will support and guide you in considering and taking up a clinical research career in this field.

Related Topics:

1) Pharmacovigilance: Common terms used in drug safety

2) Pharmacovigilance scope

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TOP 5 Clinical Research Organizations(CROs) In India

Introduction:

The clinical research industry is continuously undergoing a positive development in India. Gradually, the clinical researches are being viewed as drug discovery rather than drug development destination only. At present, many companies are looking for innovations. The famous players that are operating in the nation include MNC CROs which are dominating the country’s market . And, it is becoming important for each and every one of us to know about the popular CROs that are functioning in the nation.

This article would give an idea about some of the famous Clinical Research Organisations in the country.

The CROs that are operating in the country can be divided into two major categories:

  • Global Players with their presence in India
  • Domestic Players

Famous Global Players:

Following are a few of the famous global CROs who are having their presence in India:

Quintiles: Founded during the year 1982 when Dennis Gillings, a London based professor signed his first consulting contract. This company began its global expansion during the year 1987 and in the year 1993, the company made its entry into Asia.

Currently, this company covers the Asian continent by opening its services in around 20 cities including Bangalore, India. In our country, Quintiles has five offices in the below locations:

- Ahmedabad

-Bangalore

- Mumbai

- New Delhi

Quintiles India has the pride of holding some of the best relationships with the leading medical centers as well as with some of the experienced principal investigators.

The key services of Quintiles in India are Project Management, Clinical Trial Monitoring, Site Management, Drug Safety, Regulatory Affairs,Quality Assurance and Pharmacovigilance.

PPD: It is one among the leading clinical research organizations which was founded in the year 1985. This company has its offices in as many as 50 countries with a total number of 84 offices. In India, the company is functioning in the following three locations:

- Gurgaon

- Bangalore

- Mumbai

The clients and partners of PPD include pharma companies, medical device manufacturers, Biotech companies, academic institutions and government organizations.

And, the services that are oferred by PPD are clinical development services,laboratory services, – Consulting Services and making innovation

Paraxel: A premier provider of clinical trial services to the biopharma companies as well as the medical equipment businesses for the development of novel medical therapies across the globe for more than 30 years. Paraxel is operating in India, in the following locations:

- Delhi

-Hyderabad

- Bangalore

- Gurgaon

- Mumbai

- Chandigarh

Paraxel is offering the following services:

- Early phase services

- Phase II-III services

- Peri-approval services

- Post-approval services

- Clinical logistics services

- Consulting services

Famous Domestic Players:

Siro Clinpharm: Founded in the year 1996 by Dr. Gautam Daftary. The company started operating in Mumbai.This company also has its offices in USA and Malaysia. Various services that are being offered by this Indian CRO are:

- Clinical operations

- Clinical data management

- Medical writing

- Scientific writing

-Biostatistics as well as Statistical programming

- Clinical trial supplies

The therapeutic expertise of Siro Clinpharm includes:

- Oncology

- Cardiovascular Disease

- Central Nervous System

- Endocrinology

- Respiratory Diseases

- Infectious Diseases

GVK Bio: This is one among the Asia‘s leading discovery research and development organizations. This company has its global customer base of over 300 satisfied customers. The headquarter is located in Hyderabad. In India, the company is operating in the following locations:

- Hyderabad

- Bangalore

- Mumbai

- Gurgaon

- Ahmedabad

The services that are being offered by this CRO are:

- Discovery services

- Clinical development services

- Formulation R&D

- Manufacturing services

- Information & Analytics

- Integrated programs

Clininvent: Clinivent is the company which was established as the Contract Research Organization that is having great capabilities in the areas of clinical trial and data management. The company is located in Mumbai. The partners of this company are:

- TCG Lifesciences

- LabVantage

- Chembiotek

Various services that are being offered by this Clininvent are as follows:

- Clinical trial management

- Data management

- Pharmacovigilance

- Medical writing

- Quality assurance

- GCP training

CliniRX: CliniRX Tangent Research has been developed as an affiliate of the JK Organization which is a 125-year old entity. The JK Organization has its headquarters in India. Various services that are being offered by CliniRX are as follows:

- Site selection

- Project management

- Monitoring

- Site support

- Medical writing

- Safety surveillance

- Clinical compliance

- Biometrics

The research offices of CliniRX are located in:

- Bulgaria

- Netherlands

- United States

- Israel

In the competition of many organizations in Pune CRB Tech Solutions created a big name. Its very popular in offering the best training in Clinical Research.

Clinical research jobs demands are increasing and to meet the increasing need of excellent professionals , you should excel yourself with our clinical research institute.

This Clinical Research review by CRB Tech Solutions will help you in considering a clinical research career in this field.

Related Topic:

1)Clinical Research and Scandals

2)Clinical Trials : In The Clouds

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Hexoskin: Clothings That Records Medical Data

Clothings are sensors in the new age!

Can you imagine that there might be clothes that could record many of the things going on underneath the skin. Bygone are the days when bulky heart rate monitors provided inaccurate information. The newest thing to hit the active wear market is the Hexoskin Smart shirt. A smart shirt that is designed to give a causal person exercising to high performance athletes; lab quality results about their bio metric data.

It measures anything about an individual that includes VO2 max, heart rate, heart rate variability,breathing rate and volume as well as steps, cadence and calories. According to American Council of Exercise, knowing an individual’s target heart rate is significant to understand the intensity level of one is currently working out at.

There are possibilities that a person can easily injure themselves if they are exercising too intense or might wonder why not getting the results they want because the activity is not challenging enough. Hexoskin precisely measures a person’s heart rate, leaving no question or guesswork.

Working of Hexoskin Smart shirt

Sensing elements collect data in the shirt, which is then sent to a small device that is non-bulky and sits pretty well in the shirt’s side pocket. This small device collects all the data and is sent to Hexoskin’s secure storage servers irrespective of whether the user has a smart device nearby or not. Then, an individual can review the data at any convenient time . If there is a phone or tablet in range, the data gets streamed in real time to the device’s display.

Reports says that in the United States over 80% of adults do not meet the guidelines for both aerobic and muscle-strengthening activities. The Hexoskin Smart shirt is a kind of motivation helping adults exercise more, because seeing the results in a tangible way on a tablet or phone can be very helpful in tracking exercising habits. A person can understand where their strengths and weaknesses lie, and in turn, change their workout regime accordingly so they can make the most of their time and begin seeing real results with whatever their goal might be.

Knowing a professional athlete’s statistics has become very important. In words of Haydn Masters they thought the majority of injuries just happened. Now they knows they can prevent them and predict them. He added that with enough data, trainers can even predict what will happen to an athlete based on previous events, preventing possible injuries. This is a valuable device in the world of sports, but it can also help anyone who decides to wear Hexoskin Smart.

The information gathered from the Hexoskin Smart shirt proves to be beneficial when going to the doctor, as the results are so accurate that a medical professional could use those results to a person’s advantage when getting a check-up.

So could this “smart” shirt even help with sleeplessness? The National Sleep Foundation added that exercising regularly makes it easier to fall asleep and contributes to sounder sleep. Amazingly, the Hexoskin shirt and device can also be worn while sleeping, helping the user to better understand their sleeping habits and in turn do some correction if required.

The old fashioned belts and monitors as bio metric tracking systems are a thing of the bygone era. The smart shirt is a completely revolutionary way to track the bio metric data of the human body. Getting the information available in real-time, as well as recorded, makes it easy to understand both an individual’s waking and sleeping hours. The device is beneficial to both the wearer and their physicians and trainers.

In the race of many organizations CRB Tech Solutions has created a big name. Its very popular in offering the best Clinical Research training. This clinical research institute has created a niche for itself in this field.

Clinical research jobs are increasing rapidly in Pune and to meet the emerging need of efficient professionals , you should consider optimizing yourself with clinical courses.

The Clinical Research review by CRB Tech Solutions will help and guide you in obtaining your clinical research career.

Related Topics :

1) Top 10 Clinical Research Companies in Pune

2) CRB Tech in Clinical Research: Making a difference

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A Drought in Antibiotic Discovery

A Drought in Antibiotic Discovery

The year 1928 saw a major medical breakthrough owing to Flemming’s serendipitous discovery of penicillin, which was later claimed as the 20th century miracle drug. But the impact of this discovery was not well understood until the 1940s, when its application as a therapeutic agent was made possible by Florey and Chain.

Blamed for this late realization was the lack of biochemical and microbiological expertise at that time, as well as the lack of interest and support from the scientific community brought about by previous experience with the failure of pyocyanase and the toxicity of Salvarsan.

A-Drought-in-Antibiotic-Discovery

In 1935, a breakthrough that covered the era of antibacterials was made by the German biochemist Gerhard Domagk at the Bayer Laboratories of the I.G. Farben company in Germany. He discovered and developed the first sulfonamide, a synthetic red dye popularly known by its trade name of Prontosil, the first commercially available antibacterial.

The clinical successes resulted in a sharp decline in mortality due to killer diseases such as meningitis, child bed fever and pneumonia. Domagk’s discovery saved many lives, including prominent figures such as Winston Churchill and Franklin D. Roosevelt, Jr., son of then US President Roosevelt.

Inspired by the groundbreaking work of Domagk and Fleming, Florey and Chain, a number of subsequent antimicrobial discoveries quickly followed. Nowadays, newer antimicrobial compounds continue to be discovered and introduced, although the rate has slowed considerably.

According to an analysis done by a known magazine, large pharma companies spend approximately $5 billion to bring one new drug to market. About $350 million of the cost is to bring the drug to market, the rest is the money spent on drugs that fail safety or efficacy clinical trials, thus a pharma company must recoup the billions that they lose on failed drugs by the one drug that makes it to market.

A lot of money spent and pharmaceutical companies recoup more of their money on drugs like antidepressants and anti-inflammatories because they can be used regularly and not lose their effectiveness. That is not the case with antibiotics.

Antibiotics are very costly to develop and they can lose their power to fight infections with time. How? The bacterium that survived and is antibiotic-resistant is the one that begins reproducing in the body, thus the antibiotic originally used is no longer effective and a new antibiotic is needed to fight the mutated bacteria.

In the past five years the FDA has approved two systemic antibiotics. This is a drop of 88% since the mid-1980s.

While the benefits of the GAIN act are great, it seems that there is still a steady decline of new antibiotic development that has worried many institutions and organizations such as the World Health Organization (WHO) which stated that we’re in a competition against time to develop new antibacterials.

The small biotechnology companies are bringing new antibiotics to the market and it appears that the Center for Disease Control is pushing hospitals to enact antibiotic stewardship programs to make sure that such medicines are only used when they are really required. Dr. Tom Frieden of the CDC stated that antibiotic prescription can save patients’ from deadly infections and protect lifesaving remedies for tomorrow’s patients.”

Clinical research jobs are increasing and to meet the increasing need of efficient professionals , you should consider excelling yourself with training in Clinical Research

This Clinical Research review by CRB Tech Solutions will help you in taking a clinical research career in this field.

Related Topics:

1) Pharmacovigilance: Common terms used in drug safety

2) Pharmacovigilance scope

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Lazy Ways to be Healthy

Lazy Ways to be Healthy Being healthy could be a huge challenge, especially if you don’t have the time or the energy. But with some small changes to your life where you can improve your health and yet be lazy. Eat differently, exercise just a little bit more, and make a few other small changes to your life to improve your health without not making huge changes to your everyday life.

Lazy-Ways-to-be-Healthy

Eating and living healthier are great things to be doing, but what if it just seems like so much work. What about those who are lazy? Any hope?

Yessss!

Now eating only fruits and vegetables, looks so monotonous. Every time you need to eat and do things like wash grapes and cut celery. Spend the $6 on some reusable plastic containers or bags and in a few minutes you can wash, chop and package in bulk. You’re left with per-portioned snacks that take no work other than grabbing them from the fridge and opening the container.

As any coffee addict will say, coffee can cure many illness, but do you know it can also help to burn more fat in a workout. Studies reveal that a cup of black coffee before exercise can open the gates for your body to use more fat cells as energy. Bonus lazy points: use a coffee maker with a clock on it so it’s already brewed and waiting for you when you wake up in the morning.

Do you remember childhood days when your mom would make you layout your clothes for school the night before? Scientifically not related though. But good old mom was a bit of genius. By putting your gym clothes out the night before it saves time by cutting out searching through drawers and it removes the excuse to stay in bed because your gear is already laid out and waiting. It’s a small way to encourage yourself onto that treadmill. Well to step that laziness up to expert level you can sleep in your workout clothes.

Having insomnia? You might be too hot. Not the hotness which could rund in your mind; we are talking about heat. Reports say that you can promote better sleep by turning the thermostat down to 65 degrees Fahrenheit (that’s approximately 18 degrees Celsius for our friends outside the US). So, switch on that A/C and grab a blanket because you are heading for a great night’s sleep or a great afternoon’s nap.

Get a pet to improve your health

If you want big health results without any big effort, getting a pet could be a wise way out. Multiple researches have shown that pet owners have improved physical and mental health, including lowered BP, better ability to cope with adverse life effects, and lowered stress levels.

Exercise while watching TV

Vegging out in front of the TV set is the quickest way to pile on the pounds. However, to boost your fitness while watching TV, try squeezing a mini-workout into each commercial break. You can try from push ups to skipping or a jogging , there are plenty of measures to introduce activity into your TV-watching schedule.

So, now you’ve seen some excellent ways to be healthy even when you’re lazy! If you’ve got more excellent ideas leave a comment below. In the competition of many institutes CRB Tech Solutions created a unique name. Its well known in offering the best training in Clinical Research.

Clinical research jobs are rapidly increasing and to meet the increasing need of efficient professionals , you should think about improving yourself with our clinical research institute.

This Clinical Research review by CRB Tech Solutions will guide you in considering a clinical research career in this field.

Related Posts:

1) What is Clinical Research Organization and jobs in a CRO
2) Pharmacovigilance (GpvP) Training

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The Suboxone Challenge

People who works in pain or addiction research might be familiar with a Naloxone Challenge, when a patient is administered the opioid antagonist drug naloxone to determine if they are opioid dependent, but in this blog we introduce you to the social issue facing many addicts, which is termed as the Suboxone Challenge.

In the Journal of Clinical Pharmacology there is an article by Dr. Lorraine Rusch of Vince & Associates Clinical Research which explains a widespread issue facing the US today – the opioid addiction

According to the reports of the Institute of Addiction Medicine,though the population of the US is lesser than 5% of the global population, 80% of the opioids and 90% of the hydrocodone used worldwide is used by Americans. AS per estimates of Centers for Disease Control and Prevention, 2.2 million Americans abuse opioids and 1.8 million are dependent on them, thus they are not able to stop taking them without going into withdrawal. That’s approximately 4 million people in the US who are either abusing or addicted to prescription opioids. To put that in perspective for you, it’s the population of Oregon.

So, how do these people could get help for their addiction? Presently, treatment options in the US are extremely limited for substance abusers. There is an exceptionally good article in The Huffington Post, “Dying to be Free,” about the challenges abusers face when looking into treatment choice.

Historically, there has been a lot of resistance to the usage of Suboxone (a drug made with buprenorphine hydrochloride which helps in reducing the symptoms of opioid dependence), which many in the medical world see as the best treatment available. The thought process behind the resistance to Suboxone is numerous physicians and addiction counselors along with many members of the legal system believe that abstinence is the preferred treatment as with alcohol addiction. The author of “Dying to be Free” discusses the insufficiency of the 12-step program used for alcoholics when translated for opiate addicts. But why? When a person abuses opioids for extended periods of time their brain function is altered. Their brain changes literally.

So, what is the state of Suboxone? Why is it so difficult to get this treatment to the patients who requires it? While the National Institute on Drug Abuse has tried to increase the use of Suboxone and Methadone, many places have pushed back by limiting the number of physicians allowed to prescribe these drugs and limit the amount of times they can prescribe it in a year. Because of excessive regulation and the fear of non-compliance, it’s not surprising there is a shortage of doctors in addiction medicine.

So where does the future see? It’s really in the hands of government agencies like NIDA and the US Department of Health and Human Services who are committed to understanding addiction and working with the biopharma companies to fight this problem. Vince & Associates Clinical Trials conducts multiple Human Abuse Liability and Abuse Deterrent Formulation clinical researches each year and stands with the government and innovative companies to develop new medications that can help in reducing the rates of opioid addiction and abuse while still providing pain relief to those who need it.

There are only a few clinical trial organizations in Pune, and CRB Tech Solutions has created it’s own niche. Its known to gives the best Clinical Research training.

Clinical research jobs are increasing fast in Pune and to meet the emerging need of good professionals , you should consider increasing your efficiency with clinical courses.

The Clinical Research review by CRB Tech Solutions will guide you in obtaining your clinical research career.

Related Topics:

1)5 Ways ResearchKit Is Revolutionizing Clinical Research

2)Crowd funding In Clinical Research

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Creating Effective Relationships with CROs

Creating Effective Relationships with CROs With much development in the field of clinical research, in recent years , pharmaceutical companies have applied more focus on core competencies and relied on clinical research organizations (CROs) to support their analytical and manufacturing requirements.

In today’s economic environment, many pharma companies are using the services provided by CROs. Outsourcing analytical services can lessen overheads by circumventing the need to invest in expensive technology and equipment, thus producing cost savings for the company. The CRO can offer expertise using updated technology supported by an extensive knowledge of the current rules and regulations. Outsourcing can also save time, which is often critical because delay in production processes or batch releases, or even gaining approvals from regulatory bodies can severely destroy a company’s prospects.

Creating-Effective-Relationships-with-CROs

Drug development is an entrepreneurial venture, fostered by a passion for scientific discovery of new medications to help patients. The focus is to commit the right resources to reach the end goal of providing life-saving novel drugs to patients in quick time and with effective cost.

A successful partnership with a CRO starts with a shared goal and passion for delivering good treatment. A CRO partner with a track record of being steady, low-employee turnover and long-standing relationships with customers can establish a solid base for a new business relationship.

The biopharma market faces a lot of challenges where pace and quality are key elements in successfully getting a product from lab to market. The ability for pharma and biotechs to progress a compound more rapidly and safely through each phase of research without sacrificing safety as well as quality is essential to maximizing revenues.

One way you can help to reduce costly delays and maximize speed while maintaining quality is to build an effective relationship with CROs conducting clinical research. The key word here is effective. The idea is of not talking about simply having a preferred provider in place or the like, rather a true relationship where a sponsor is at ease doing more than just rewarding a study and have confidence in the CRO they will partner with.

You could think of it this way, Clinical research units conduct clinical trials. What we’re saying is that conducting clinical trials is their specialty. It’s what they does, every day for 365 days in a year. Why wouldn’t you trust the expertise of such a resource to aid you by reviewing a protocol, assist with an adaptive design for a study or discuss the operational conduct of your specific trial?

By combining several protocols into a single umbrella protocol, sponsors can assess multiple endpoints and gain multiple objectives at once, which translate into both time and cost savings. Working effectively with a CRO helps companies to efficiently manage their drug development pipeline by looking at study designs and operational possibilities which in turn can help sponsors to determine where time and money can be used most successfully.

The most significant aspect in creating an effective relationship with a CRO is to develop open and persistent lines of communication. Being able to properly communicate is the essence of a true cooperation and it is invaluable because it can reduce costly delays from protocol concerns, recruitment problems, clinical conduct and other important milestones. By keeping a line of communication current and open, faith and rapport are built with the CRO. A dedication to rapid responsiveness by a CRO can build a sense of being part of a sponsor’s organization which can lead to better study conduct and hopefully reduce costly delays.

In the competition of many organizations CRB Tech Solutions created a big name. Its best known in offering the best training in Clinical Research.

Clinical research jobs are increasing and to meet the increasing requirement of efficient professionals , you should think of improving yourself with our clinical research institute.

This Clinical Research review by CRB Tech Solutions will help you in considering a clinical research career in this field.

Related Posts:

1) Clinical Research Organization

2) What is Clinical Research Organization and jobs in a CRO

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Bio-similars and the Everyday Men

Bio-similars are gaining popularity with ongoing various clinical research worldwide. What are Bio-similars ? And why the general consumers should care about them?

As explained by the FDA, a biosimilar is a biological product that is approved based on the fact that it is highly similar to an FDA-approved biological product. Biosimilars are like generics, which are drugs that are identical to a brand name drug in dosage form,strength,safety, way to administration, quality and intended use. But there is a difference between generics and biosimilars. It includes the complexity of the molecule, manufacturing and unlike generics, biosimilars are not the exact replicas of the reference drug. Hence, data required by regulatory agencies to prove similarities and obtain approval is more challenging.

Bio-similars-and-the-Everyday-Men

The pharma sector is concerned about biosimilars because, as per BioPharm International, sales of biologics have gained from $20 billion in 2000 to $159 billion in 2014. As per reports, biologics represent about 70% of the worth of the top 10 selling drugs in the world. With an approximate 19% increase in sales across the global drug market over the last 14 years there is an expectation of continuous growth, biologics and biosimilars representing billions of dollars in revenue over the coming years. Forbes reported that the sector expects 10 of the top 20 global bestselling drugs in 2016 could be biologics.

That sounds great for pharma companies, but why should the average mankind care about biosimilars? Very simple: health and money matters.

Biosimilars have the power to save the healthcare system money because they are lesser in cost than the reference drugs. Moreover, Bio-similars have the ability to become a significant economic driver for the industry; as the Frost & Sullivan analysis predicts exponential growth over the next decade.

Biosimilars may also improve the outlook for patients since they have the potential to be significantly less expensive than their biologic counterparts, thereby making them more available to the people who require them like the elderly and the not-insured or under-insured. Biologics and their biosimilar counterparts are made used to treat a broad range of diseases including dermal conditions, cancer, low WBC counts, rheumatoid arthritis, anemia and many to mention.

The ramifications for clinical trials are vast as well. Biologics, by nature of their composition are large molecules and very complex products. Additionally, they’re extremely sensitive to the locations of where and how they’re produced. Fortune compares them to snowflakes, where the molecular makeup of each biosimilar treatment will appear unique, like individual snowflakes, even though they have similar results. This is how biosimilars are different than generics. You might have two biosimilars for the same drug with the same usage, but molecularly they will look different and may act unique.

Not every clinical research unit can carry out studies with biologics since they require high safety assessment capabilities, on site physicians to assess clinical trial volunteers daily and a rigorous quality control department.

You might or might not have heard very much about biosimilars before, but you could definitely expect to hear more and more about them in the coming times. With many of the leading biologic medications dropping off the patent cliff by 2020, the world will be seeing the benefits of biosimilars sooner as per assumptions.

If you are seeking for Clinical research course in Pune, then CRB Tech Solutions has created a name for itself. Its known for providing the best training in Clinical Research.

Clinical research jobs are rapidly gaining prominence and to meet the need of efficient professionals , you should consider optimizing yourself with our institute of clinical research.

The Clinical Research review by CRB Tech Solutions will help you support your clinical research career .

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Clinical Research Volunteers Are The Real Heroes

Clinical trials is being possible owing to the volunteers!

Hence recruiting volunteers for a clinical research is vital to its success, but once volunteers are in house it’s primary to retain them through the duration of the study. Also, there is one in-house period or several where the volunteer must return to the clinic unit for several night stays.

So, the question as a clinical research site, how do you keep your study volunteers happy and keep them for the whole length of the trial?

The people both men & women volunteer for clinical research which is conducted for the benefit of global health. Hence it’s significant to ensure that the volunteers are safe, at ease and willing to fulfill the study needs. Thus the unparalleled recruitment and retention rates can be credited to the top class staff and state-of-the-art facilities.

Think about it from the point of a volunteer. You register to be in a study with an in-house period of fourteen nights. What do you do for those days away from home? Though, sleeping and study procedures would take up a few hours of the day, but what about the other hours a day? Also, you’re being compensated for each day you stay, that’s true, but wouldn’t you be more likely to stay if you had access to the latest movies and TV shows, video game systems, high-speed Wi-Fi and delicious meals prepared for you?

It’s very important for biopharmaceutical clients to get reliable study data for their early phase clinical trials, mainly those complex healthy normal volunteer trials and adapting designs involving patients. It’s equally important to offer the best experience possible for the study volunteers. They helps in the mission to invest in the future of clinical research for the benefit of global health and help find cures for people who are suffering .

It would be very human to view the volunteers as heroes because they are the key to helping save human lives one at a time.

Clinical research long required its public service campaign that is recognizable and that can engage the public in thinking differently about clinical trial. Clinical Heroes is exactly that.

For the general public, clinical trial is not typically a dinner table conversation. It’s even not discussed in high school science classrooms. It’s only discussed in a physician’s office when a patient is diagnosed with an illness. Hence clinical research touches every man’s life regularly.

According to the reports, many people are taking prescription medications at the present time and most report routinely using over-the-counter medications. But , the general public does not connect the medicines and behavioral interventions it consumes to the clinical trials and dedication of volunteers before them who made these developments possible by taking life risk.

Moreover while an estimated billion dollars is spent annually on mass-media patient recruitment advertisement and promotion, and they are met with a large amount of indifference because they have no base on which to rest. The public has no context to understand the importance of clinical trial.

Extensive media coverage of drug withdrawals and their aftermath; conflicts-of-interest among authorized members and research professionals; questionable pricing practices; and fatal errors resulting in harm to patients, have left the public confused and troubled.

While, recently, perception has improved slightly, the late response by the clinical research community has led us to a point of poor public perception and eroding public trust.

In the competition of many organizations CRB Tech Solutions created a big name. Its well known in offering remarkable training in Clinical Research.

Clinical research jobs are increasing and to meet the increasing need of efficient professionals , you should think about improving yourself with our clinical research institute.

This Clinical Research review by CRB Tech Solutions considering a clinical research career in this field.

Related Topics:

1)Clinical Research training in CRB Tech

2)Clinical research training course in CRB Tech

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What Really Happens in a Clinical Lab ?

What Really Happens in a Clinical Lab ? Have you ever wondered what actually goes on inside a clinical research unit? Well this article would give you some insight in general!

The essential aspect of a Clinical Research unit is the laboratory and the lab team.

In the clinical facilities, laboratory experts might be both men and women. They are responsible for protocol review, creating documents for the lab, labeling and setting up all requirements for sample collection, processing them and shipping them to respective labs worldwide, or get them in their own labs if the equipments are available.

They process many samples every month, which includes blood, urine, stool and saliva going through the lab on a daily basis. The busiest hour is during the morning when protocols often dictate tight timeliness for sample collection.

Lab staff must work together with the clinical teams to ensure that blood samples are collected, handled properly and make them to the centrifuge and the refrigerators in time. It is very essential for each and every tube to be labeled correctly and processed promptly.

Some clinical labs, use a Watson sample tracking system, which allows the team to track every single test tube as it is processed through the clinic, into the freezer, and then into shipping. Watson helps the lab teams to create tube labels and barcodes for aliquot tubes, track storage, and create shipping manifests. These ensures that every sample is handled appropriately and quality samples are processed for every study.

All the equipment are calibrated regularly and continually monitored for quality analysis. In some labs, refrigerators and freezers are monitored with a Rees temperature monitoring system, which notes the temperature every 5 minutes and alerts the staff with an email and phone call when temperatures vary from the range.

The clinical staff plans in order to make sure that the thousands of samples are kept straight. Moreover quality control looks over the plans and source documents. Maintaining quality data is the mission, and with a vigilant lab team the mission gets accomplished.

In many facilities, it is open 24/7 with a capacity to analyze over 50,000 study samples per month! There are 15% of resources allocated for R&D, 30+ scientists are dedicated for developing complex methods for small molecules, oligonucleotides, biomarkers, proteins, and peptides.

They also have the scientific evaluation/knowledge to advise sponsors on the appropriate assay platform.

The clinical research labs are proud of the quality and innovative work of the scientists and analysts! They are credited to analyze over 400,000 samples each year and access numerous methods.

Many clinical labs develop robust bioassays for novel molecular entities and commercially available compounds analyzed in various biological fluids and tissues for various animals and humans.

In your University days, the students should try to arrange a visit to organizations and institutes where good clinical research is undertaken. This would add more to your knowledge and also practically help you in pursuing your career. Sometime things are different from what we read in books. A practical hands on in a specific environment would help you to nurture your knowledge and enhance your skill. It would be very exciting and inspiring to watch the experts making plans, playing with the samples and managing a well planned database.

If you are seeking for Clinical research course in Pune, then CRB Tech Solutions has created a niche for itself. Its very popular in offering the best training in Clinical Research.

Clinical research jobs are rapidly increasing and to meet the emerging need of efficient professionals , you should consider optimizing yourself with our institute of clinical research.

The Clinical Research review by CRB Tech Solutions will help you in considering a clinical research career in this field.

Related Posts: 

1) How Clinical Research Management Can Help You?

2) Get hired quickly as clinical research professional

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